Applications for postdoctoral fellowships are being considered for organic chemists or medicinal chemists who are U.S. citizens or permanent residents. Applicants must have a good background in synthetic organic chemistry. The position would carry a maximum of three years of support. The project would involve structure-based design and synthesis of selective opioid ligands, and would include substantial interaction with scientists who are working on site-directed mutagesis and molecular modeling of opioid receptors. Qualified applicants should forward their cv and the names of three scientists who are familiar with their background and research to: Prof. Philip S. Portoghese, Dept. of Medicinal Chemistry, University of Minnesota, 308 Harvard St. S.E., Minneapolis, MN 55455.

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